p21-activated kinases as viable therapeutic targets for the treatment of high-risk Ewing sarcoma
Sign Up to like & getrecommendations! Published in 2021 at "Oncogene"
DOI: 10.1038/s41388-020-01600-9
Abstract: Ewing sarcoma (ES) is the second most common bone tumor in children and young adults. Unfortunately, there have been minimal recent advancements in improving patient outcomes, especially in metastatic and recurrent diseases. In this study,… read more here.
Keywords: p21 activated; risk; high risk; activated kinases ... See more keywords
Is Mitochondrial Oxidative Stress a Viable Therapeutic Target in Preeclampsia?
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11020210
Abstract: Despite considerable research efforts over the past few decades, the pathology of preeclampsia (PE) remains poorly understood with no new FDA-approved treatments. There is a substantial amount of work being conducted by investigators around the… read more here.
Keywords: stress; therapeutic target; oxidative stress; mitochondrial oxidative ... See more keywords