In-Vial Detection of Protein Denaturation Using Intrinsic Fluorescence Anisotropy
Sign Up to like & getrecommendations! Published in 2023 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.2c03912
Abstract: The conventional quality control techniques for identifying the denaturation of biopharmaceuticals includes sodium dodecyl sulfate-polyacrylamide gel electrophoresis for identifying fragmentation, ion exchange chromatography and isoelectric focusing for identifying deamidation, reverse-phase high-performance liquid chromatography (HPLC) for… read more here.
Keywords: intrinsic fluorescence; vial detection; protein denaturation; denaturation ... See more keywords