Intra-Vial Heterogeneity in Physical Form of Mannitol in Colyophilized Binary Systems
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DOI: 10.1007/s11095-018-2499-x
Abstract: AbstractPurposeTo study spatial heterogeneity in phase composition when mannitol is co-lyophilized with non-crystallizing lyoprotectant, such as sucrose or trehalose. To study the influence of formulation composition and processing conditions on the extent of mannitol hemihydrate… read more here.
Keywords: vial heterogeneity; mhh; phase; heterogeneity ... See more keywords