Direct Amination of Cobaltocenium Hexafluoridophosphate via Vicarious Nucleophilic Substitution
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DOI: 10.1021/acs.organomet.9b00205
Abstract: In this communication we report a convenient, as short as possible synthesis of aminocobaltocenium hexafluoridophosphate, a very useful compound for further functionalization in cobaltocenium chemistry. Via vicarious nucleophilic substitution of hydrogen of cobaltocenium hexafluoridophosphate with… read more here.
Keywords: vicarious nucleophilic; hexafluoridophosphate; via vicarious; nucleophilic substitution ... See more keywords
Alkylation of Nitropyridines via Vicarious Nucleophilic Substitution
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DOI: 10.1021/acs.orglett.1c03920
Abstract: Electrophilic nitropyridines react with sulfonyl-stabilized carbanions to give products of C–H alkylation via vicarious nucleophilic substitution. The process consists of formation of the Meisenheimer-type adduct followed by base-induced β-elimination of the sulfinic acid (e.g., PhSO2H).… read more here.
Keywords: nitropyridines via; vicarious nucleophilic; via vicarious; alkylation nitropyridines ... See more keywords
α-Fluorination of Nitrobenzenes and Nitropyridines via Vicarious Nucleophilic Substitution of Hydrogen
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DOI: 10.1055/s-0039-1690862
Abstract: A highly selective C–H functionalization of nitrobenzenes and nitropyridines is reported using tandem vicarious nucleophilic substitution (VNS) chemistry with electrophilic fluorination using Selectfluor®. The process generates tertiary benzylic fluorides in good yield under simple, mild… read more here.
Keywords: fluorination nitrobenzenes; nucleophilic substitution; vicarious nucleophilic; nitrobenzenes nitropyridines ... See more keywords