LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "vicinal diamines" as a keyword



Photo from academic.microsoft.com

Vicinal Diamines as Smart Cosubstrates in the Transaminase-Catalyzed Asymmetric Amination of Ketones

Sign Up to like & get
recommendations! Published in 2017 at "European Journal of Organic Chemistry"

DOI: 10.1002/ejoc.201700253

Abstract: Transaminases (TAs) have recently been established as catalysts for the asymmetric, reductive amination of prochiral ketones. Depending on the ketone substrate and the amine donor (the cosubstrate), equilibrium constants may limit high conversions; thus, methods… read more here.

Keywords: cosubstrates transaminase; diamines smart; transaminase catalyzed; smart cosubstrates ... See more keywords

One-Pot Aminoalkylation of Aldehydes: Diastereoselective Synthesis of Vicinal Diamines with Azaarylmethylamines.

Sign Up to like & get
recommendations! Published in 2019 at "Organic letters"

DOI: 10.1021/acs.orglett.9b03287

Abstract: A one-pot synthesis of vicinal diamines with azaarylmethylamines and aldehydes is reported. A diverse array of vicinal diamines could be achieved in up to 92% yield with good to excellent diastereoselectivities (up to 20:1). The… read more here.

Keywords: synthesis vicinal; diamines azaarylmethylamines; vicinal diamines; one pot ... See more keywords

Regioselective intermolecular carboamination of allylamines via nucleopalladation: empowering three-component synthesis of vicinal diamines

Sign Up to like & get
recommendations! Published in 2024 at "Chemical Science"

DOI: 10.1039/d4sc07630c

Abstract: An intermolecular carboamination reaction of allyl amines under Pd(ii)-catalysis is reported, expediting the synthesis of valuable vicinal diamines embedded in a functionally enriched linear carbon framework with high yields and exclusive Markovnikov selectivity. Central to… read more here.

Keywords: carbon; vicinal diamines; intermolecular carboamination; synthesis ... See more keywords

Rhodium-catalyzed one-pot tandem reductive amination/asymmetric transfer hydrogenation of quinoxaline-2-carbaldehydes and anilines for the efficient synthesis of chiral vicinal diamines

Sign Up to like & get
recommendations! Published in 2025 at "Organic Chemistry Frontiers"

DOI: 10.1039/d5qo00625b

Abstract: Chiral N,N′-diaryl vicinal diamines have been synthesized enantioselectively via Cp*Rh-catalyzed tandem reductive amination/asymmetric transfer hydrogenation of quinoxaline-2-carbaldehydes with anilines using HCO2H/NEt3 (5/2) as the hydrogen source. read more here.

Keywords: reductive amination; vicinal diamines; amination asymmetric; tandem reductive ... See more keywords

Photoredox-Catalyzed Radical Relay Reaction Toward Functionalized Vicinal Diamines

Sign Up to like & get
recommendations! Published in 2018 at "Synthesis"

DOI: 10.1055/s-0037-1609844

Abstract: A strategy has been described to synthesize β,γ-diamino­ketones. This strategy is enabled by photoredox-catalyzed and nitrogen-centered radical-triggered cascade reactions of styrenes, enamides, and O-acylhydroxylamines in DMSO. Four bonds (one C–C, one C–N, and two C–O)… read more here.

Keywords: relay reaction; vicinal diamines; photoredox catalyzed; functionalized vicinal ... See more keywords