Anti‐Oxidative and Anti‐Inflammatory Micelles: Break the Dry Eye Vicious Cycle
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202200435
Abstract: Dry eye disease (DED) impacts ≈30% of the world's population and causes serious ocular discomfort and even visual impairment. Inflammation is one core cause of the DED vicious cycle, a multifactorial deterioration in DED process.… read more here.
Keywords: mtem los; vicious cycle; inflammation; cycle ... See more keywords
Necroptotic TNFα‐Syndecan 4‐TNFα Vicious Cycle as a Therapeutic Target for Preventing Temporomandibular Joint Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4542
Abstract: Temporomandibular joint osteoarthritis (TMJOA) is a chronic degenerative disease for which the underlying mechanism still remains unclear. Compared with apoptosis and autophagy, necroptosis causes greater harm to tissue homeostasis by releasing damage‐associated molecular patterns (DAMPs).… read more here.
Keywords: necroptosis; vicious cycle; therapeutic target; tnf ... See more keywords
Functionalized Metal-Organic Framework-Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202206919
Abstract: The regeneration of diabetic bone defects remains challenging. Hyperglycemia causes inflammation state and excessive reactive oxygen species (ROS) during bone regeneration period. These two effects reinforce one another and create an endless loop that is… read more here.
Keywords: vicious cycle; inflammation; diabetic bone; bone defects ... See more keywords
O-GlcNAc in cancer: An Oncometabolism-fueled vicious cycle
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-018-9751-2
Abstract: Cancer cells exhibit unregulated growth, altered metabolism, enhanced metastatic potential and altered cell surface glycans. Fueled by oncometabolism and elevated uptake of glucose and glutamine, the hexosamine biosynthetic pathway (HBP) sustains glycosylation in the endomembrane… read more here.
Keywords: glcnac; oncometabolism; glcnacylation; cycle ... See more keywords
Insulin resistance in polycystic ovary syndrome phenotypes and the vicious cycle model in its etiology
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-26718-2
Abstract: Polycystic ovary syndrome (PCOS) is a multifactorial disorder driven by at least three pathophysiological components: hypothalamic, ovarian, and obesity-related mechanisms. Insulin resistance (IR) is a unifying feature. Reciprocal interactions among androgen excess, hyperinsulinemia, and reduced… read more here.
Keywords: etiology; resistance; insulin resistance; vicious cycle ... See more keywords
The Inflation in Oncology Publications and Journals: A Vicious Cycle That Needs Immediate Attention
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Investigation"
DOI: 10.1080/07357907.2023.2164894
Abstract: In academia, publications, often referred to as “academic currency”, are important for professional growth and academic promotion. Medical journals serve as the platform for medical publications, with an increase in specialized journals mirroring the shift… read more here.
Keywords: oncology publications; oncology; vicious cycle; number ... See more keywords
A vicious cycle of β amyloid–dependent neuronal hyperactivation
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aay0198
Abstract: Dissecting hyperactivation in AD Progressive accumulation of amyloid β (Aβ) in the brain is a defining feature of Alzheimer's disease (AD). At late stages of AD, pathological Aβ accumulations cause neurodegeneration and cell death. However,… read more here.
Keywords: dependent neuronal; amyloid dependent; hyperactivation; vicious cycle ... See more keywords
Inflammation and Microcalcification: A Never-Ending Vicious Cycle in Atherosclerosis?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Vascular Research"
DOI: 10.1159/000521161
Abstract: Inflammatory cells and cytokines are known for long to worsen the development of atherosclerotic plaques in mice, and intense efforts are today devoted to develop anti-inflammatory therapeutic strategies to slow down plaque development. Increasing data… read more here.
Keywords: vicious cycle; inflammation; inflammation microcalcification; microcalcification ... See more keywords
“Breaking a vicious cycle”: the reproduction of ableism in higher education and its impact on students with disabilities
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Education"
DOI: 10.3389/feduc.2024.1504832
Abstract: Despite the widespread promotion of inclusive learning environments, students with disabilities have to exert time and effort in gaining accommodations and proving themselves as competent individuals. In following up a factorial survey experiment that found… read more here.
Keywords: education; vicious cycle; higher education; students disabilities ... See more keywords
A Vicious Cycle: In Severe and Critically Ill COVID-19 Patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.930673
Abstract: The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, is one of the fastest-evolving viral diseases that has instigated a worldwide pandemic. Severe inflammatory syndrome and venous thrombosis… read more here.
Keywords: vicious cycle; critically ill; covid patients; ill covid ... See more keywords
The Vicious Cycle: Problematic Family Relations, Substance Abuse, and Crime in Adolescence: A Narrative Review
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Psychology"
DOI: 10.3389/fpsyg.2021.673954
Abstract: Despite the copiousness of studies on the risky behaviors of adolescents, we cannot establish with certainty the leading aspects involved in teens’ substance abuse and criminal actions. This review aims to explore the interplay among… read more here.
Keywords: substance; substance abuse; cycle problematic; family ... See more keywords