Substitutions near the HA receptor binding site explain the origin and major antigenic change of the B/Victoria and B/Yamagata lineages
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2211616119
Abstract: Significance Influenza viruses are estimated to infect up to 20% of people during annual epidemics, causing substantial morbidity and mortality, particularly among risk groups. Vaccines continue to be the best available preventive measure, but their… read more here.
Keywords: receptor binding; victoria yamagata; substitutions near; binding site ... See more keywords
Cross-Protective Efficacy of Monovalent Live Influenza B Vaccines against Genetically Different Lineages of B/Victoria and B/Yamagata in Ferrets
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DOI: 10.1155/2018/9695628
Abstract: Background Currently, two genetic lineages of influenza B virus, B/Victoria and B/Yamagata, are cocirculating in humans in various countries. This situation has raised a question regarding the possibility of cross-protection between B components of live… read more here.
Keywords: victoria yamagata; challenge; different lineages; influenza ... See more keywords
Patterns of influenza B circulation in Latin America and the Caribbean, 2010–2017
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DOI: 10.1371/journal.pone.0219595
Abstract: Objective There are limited published data about the circulation of influenza B/Victoria and B/Yamagata in Latin America and the Caribbean (LAC) and most countries have a vaccine policy that includes the use of the trivalent… read more here.
Keywords: victoria yamagata; influenza vaccine; lineage; influenza ... See more keywords
Vaccine Mismatches, Viral Circulation, and Clinical Severity Patterns of Influenza B Victoria and Yamagata Infections in Brazil over the Decade 2010–2020: A Statistical and Phylogeny–Trait Analyses
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DOI: 10.3390/v14071477
Abstract: Worldwide, infections by influenza viruses are considered a major public health challenge. In this study, influenza B vaccine mismatches and clinical aspects of Victoria and Yamagata infections in Brazil were assessed. Clinical samples were collected… read more here.
Keywords: infections brazil; phylogeny trait; yamagata infections; victoria yamagata ... See more keywords
Influenza A (N1-N9) and Influenza B (B/Victoria and B/Yamagata) Neuraminidase Pseudotypes as Tools for Pandemic Preparedness and Improved Influenza Vaccine Design
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DOI: 10.3390/vaccines10091520
Abstract: To better understand how inhibition of the influenza neuraminidase (NA) protein contributes to protection against influenza, we produced lentiviral vectors pseudotyped with an avian H11 hemagglutinin (HA) and the NA of all influenza A (N1–N9)… read more here.
Keywords: influenza; victoria yamagata; design; influenza influenza ... See more keywords