The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression.
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DOI: 10.1016/j.ejmech.2021.114045
Abstract: Depression is one of the most frequent comorbid psychiatric symptoms of Alzheimer's disease (AD), and no efficacious drugs have been approved specifically for this purpose thus far. Herein, we proposed a novel therapeutic strategy that… read more here.
Keywords: depression; vilazodone donepezil; triple target; donepezil ... See more keywords