Effect of Crohn’s Disease on Villous Length and CYP3A4 Expression in the Pediatric Small Intestine
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DOI: 10.1111/cts.12938
Abstract: Changes in absorptive capacity and first‐pass metabolism in the small intestine affect oral drug bioavailability. Characterization of such changes as a consequence of inflammation is important for developing physiologically‐based pharmacokinetic (PBPK) models for inflammatory bowel… read more here.
Keywords: length; villous length; cyp3a4 expression; length cyp3a4 ... See more keywords