Membrane-Bound Vimentin Filaments Reorganize and Elongate under Strain.
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.3c00025
Abstract: Within a cell, intermediate filaments interact with other cytoskeletal components, altogether providing the cell's mechanical stability. However, little attention has been drawn to intermediate filaments close to the plasma membrane. In this cortex configuration, the… read more here.
Keywords: filaments reorganize; microscopy; vimentin filaments; bound vimentin ... See more keywords
Mutation-induced alterations of intra-filament subunit organization in vimentin filaments revealed by SAXS.
Sign Up to like & getrecommendations! Published in 2019 at "Soft matter"
DOI: 10.1039/c8sm02281j
Abstract: Vimentin intermediate filaments constitute a distinct filament system in mesenchymal cells that is instrumental for cellular mechanics and migration. In vitro, the rod-like monomers assemble in a multi-step, salt-dependent manner into micrometer long biopolymers. To… read more here.
Keywords: vimentin; mutation induced; vimentin filaments; intra filament ... See more keywords
Molecular organization and mechanics of single vimentin filaments revealed by super-resolution imaging
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm2696
Abstract: Intermediate filaments (IFs) are involved in key cellular functions including polarization, migration, and protection against large deformations. These functions are related to their remarkable ability to extend without breaking, a capacity that should be determined… read more here.
Keywords: mechanics; vimentin filaments; organization; molecular organization ... See more keywords