Vinyl Carbocations Generated under Basic Conditions and Their Intramolecular C-H Insertion Reactions.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b02110
Abstract: Here we report the surprising discovery that high-energy vinyl carbocations can be generated under strongly basic conditions, and that they engage in intramolecular sp3 C-H insertion reactions through the catalysis of weakly coordinating anion salts.… read more here.
Keywords: insertion reactions; insertion; generated basic; basic conditions ... See more keywords
Catalytic asymmetric C–H insertion reactions of vinyl carbocations
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.ade5320
Abstract: From the preparation of pharmaceuticals to enzymatic construction of natural products, carbocations are central to molecular synthesis. Although these reactive intermediates are engaged in stereoselective processes in nature, exerting enantiocontrol over carbocations with synthetic catalysts… read more here.
Keywords: vinyl cation; asymmetric insertion; vinyl carbocations; insertion ... See more keywords