Regio- and Stereoselective N-addition to an Open Bromo Vinyl Cation
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DOI: 10.1016/j.tetlet.2021.153173
Abstract: Abstract A protocol for the synthesis of thus far inaccessible bromo vinyl triflimides is presented. Our previously reported concept of assisted vinyl cation formation was engaged to achieve both a protonation of relatively electron poor… read more here.
Keywords: cation; vinyl cation; stereoselective addition; bromo vinyl ... See more keywords
Catalytic asymmetric C–H insertion reactions of vinyl carbocations
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.ade5320
Abstract: From the preparation of pharmaceuticals to enzymatic construction of natural products, carbocations are central to molecular synthesis. Although these reactive intermediates are engaged in stereoselective processes in nature, exerting enantiocontrol over carbocations with synthetic catalysts… read more here.
Keywords: vinyl cation; asymmetric insertion; vinyl carbocations; insertion ... See more keywords