Articles with "vinyl esters" as a keyword



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Promiscuous Lipase-Catalyzed Markovnikov Addition of H-Phosphites to Vinyl Esters for the Synthesis of Cytotoxic α-Acyloxy Phosphonate Derivatives

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Published in 2022 at "Materials"

DOI: 10.3390/ma15051975

Abstract: An enzymatic route for phosphorous-carbon- bond formation is developed by discovering new promiscuous activity of lipase. This biocatalytic transformation of phosphorous-carbon- bond addition leads to biologically and pharmacologically relevant α-acyloxy phosphonates with methyl group in… read more here.

Keywords: phosphites vinyl; vinyl esters; lipase; markovnikov addition ... See more keywords