Concise Total Synthesis of (±)-Deguelin and (±)-Tephrosin Using a Vinyl Iodide as a Key Building Block.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.7b00794
Abstract: A concise and protecting-group-free total synthesis of the antiproliferative natural product (±)-deguelin (2) was accomplished in four steps and 62% overall yield from commercially available precursors. The key transformation employed a vinyl iodide as the… read more here.
Keywords: total synthesis; vinyl iodide; deguelin; building block ... See more keywords
Vinyl Iodide Containing Polymers Directly Prepared via an Iodo-yne Polymerization
Sign Up to like & getrecommendations! Published in 2020 at "ACS Macro Letters"
DOI: 10.1021/acsmacrolett.9b00979
Abstract: Postpolymerization modifications are a prominent route for tuning polymer properties and diversifying materials. Thus, polymers containing robust chemical handles are desirable. Vinyl iodide functionality is commonly enlisted for selective transformations on small molecules, but these… read more here.
Keywords: containing polymers; iodide containing; vinyl iodide; iodo yne ... See more keywords