Pd-catalyzed stereoselective tandem ring-opening amination/cyclization of vinyl γ-lactones: access to caprolactam diversity†
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DOI: 10.1039/d0sc03647a
Abstract: A stereoselective amination/cyclization cascade process has been developed that allows for the preparation of a series of unsaturated and substituted caprolactam derivatives in good yields. This conceptually novel protocol takes advantage of the easy access… read more here.
Keywords: ring opening; amination; amination cyclization; vinyl lactones ... See more keywords