Highly Regioselective C–H Alkylation of Alkenes Through an Aryl to Vinyl 1,4-Palladium Migration/C–C Cleavage Cascade
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DOI: 10.1021/acscatal.9b04161
Abstract: Palladium-catalyzed C−H alkylation of gem-disubstituted ethylenes has been efficiently achieved with cyclobutanols as the coupling partners through an aryl to vinyl 1,4-palladium migration/ring-opening C–C cleavage cascade, giving trisubstituted alkenes in high yields. The protocol features… read more here.
Keywords: cleavage; palladium migration; aryl vinyl; palladium ... See more keywords