Intramolecular Cyclizations of Vinyl-Substituted N,N-Dialkyl Arylamines Enabled by Borane-Assisted Hydride Transfer
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b04485
Abstract: Catalytic amounts of B(C6F5)3 have been found to be able to promote the intramolecular cyclization of vinyl-substituted N,N-dialkyl arylamines to afford nitrogen-containing heterocycles. Our mechanistic studies indicate the reaction is initiated by abstraction of an… read more here.
Keywords: hydride; substituted dialkyl; dialkyl arylamines; intramolecular cyclizations ... See more keywords
Cascade aryne insertion/vinylogous aldol reaction of vinyl-substituted β-keto/enol carbonyls.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06810e
Abstract: Cyclic and acyclic vinyl substituted β-keto/enol carbonyl substrates, on reaction with arynes, result in differentially substituted naphthyl carbocycles, hitherto difficult to synthesize with existing protocols. While the substitutions on the arynes have no role, the… read more here.
Keywords: keto enol; vinyl substituted; keto; substituted keto ... See more keywords
Synthesis of vinyl-substituted alcohols using acetylene as a C2 building block
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc06400f
Abstract: Vinyl-substituted alcohols represent a highly useful class of molecular skeletons. The current method typically requires either stoichiometric metallic reagents or preformed precursors. Herein, we report a nickel catalysis-enabled synthesis of vinyl-substituted alcohols via a 5-membered… read more here.
Keywords: alcohols using; synthesis vinyl; vinyl substituted; substituted alcohols ... See more keywords