Enantioselective Synthesis of Atropisomers via Vinylidene ortho-Quinone Methides (VQMs).
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.2c00486
Abstract: ConspectusAtropisomers, arising from conformational restriction, are inherently chiral due to the intersecting dissymmetric planes. Since there are numerous applications of enantiopure atropisomers in catalyst design, drug discovery, and material science, the asymmetric preparation of these… read more here.
Keywords: enantioselective synthesis; chemistry; vinylidene ortho; synthesis ... See more keywords
Vinylidene ortho-Quinone Methides: Unique Chiral Reaction Intermediates in Catalytic Asymmetric Synthesis.
Sign Up to like & getrecommendations! Published in 2018 at "Chimia"
DOI: 10.2533/chimia.2018.892
Abstract: Vinylidene ortho-quinone methides (VQMs) are one-carbon elongated homologues of ortho-quinone methides (QMs), well-known as useful reaction intermediates in organic transformations. These related quinone methides are quite distinct in terms of stereochemistry. Namely, VQMs are characterized… read more here.
Keywords: ortho quinone; reaction intermediates; vinylidene ortho; quinone methides ... See more keywords