VIP interneurons regulate olfactory bulb output and contribute to odor detection and discrimination.
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1016/j.celrep.2022.110383
Abstract: In the olfactory bulb (OB), olfactory information represented by mitral/tufted cells (M/Ts) is extensively modulated by local inhibitory interneurons before being transmitted to the olfactory cortex. While the crucial roles of cortical vasoactive-intestinal-peptide-expressing (VIP) interneurons… read more here.
Keywords: odor; vip interneurons; detection; olfactory bulb ... See more keywords
Selective ablation of VIP interneurons in the rodent prefrontal cortex results in increased impulsivity
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0286209
Abstract: It has been well-established that novelty-seeking and impulsivity are significant risk factors for the development of psychological disorders, including substance use disorder and behavioral addictions. While dysfunction in the prefrontal cortex is at the crux… read more here.
Keywords: selective ablation; prefrontal cortex; vip interneurons; ablation vip ... See more keywords