Viperin protein inhibits the replication of caprine parainfluenza virus 3 (CPIV 3) by interaction with viral N protein.
Sign Up to like & getrecommendations! Published in 2020 at "Antiviral research"
DOI: 10.1016/j.antiviral.2020.104903
Abstract: Caprine parainfluenza virus type3 (CPIV3) is a newly identified member of Paramyxoviridae family. CPIV3 is highly prevalence in China and showed pathogenecity to goats; in addition, CPIV3 infection causes severe clinical disease under stress and/or… read more here.
Keywords: protein; cpiv3; viperin; viral protein ... See more keywords
TRIM33 promotes spring viremia of carp virus replication by degrading the antiviral protein viperin_sv1
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.736837
Abstract: Abstract TRIM33 is a member of the tripartite motif (TRIM) superfamily which contributes to regulate a multitude of cellular processes, including innate immune responses. Viperin_sv1 has recently been identified as a novel splice variant of… read more here.
Keywords: trim33; replication; viperin; viperin sv1 ... See more keywords
Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular cell"
DOI: 10.1016/j.molcel.2022.02.031
Abstract: Innate immune responses induce hundreds of interferon-stimulated genes (ISGs). Viperin, a member of the radical S-adenosyl methionine (SAM) superfamily of enzymes, is the product of one such ISG that restricts the replication of a broad… read more here.
Keywords: viperin triggers; viperin; ribosome collision; translation inhibition ... See more keywords
Production of polyclonal viperin antisera using N-terminal deleted recombinant bovine viperin.
Sign Up to like & getrecommendations! Published in 2022 at "Animal biotechnology"
DOI: 10.1080/10495398.2022.2120890
Abstract: Viperin, also known as radical S-adenosyl methionine domain-containing protein (RSAD2) is a multifunctional interferon-stimulated gene (ISG) that is activated during the viral infections. Viperin belongs to S-adenosyl methionine (SAM) superfamily of enzymes known to catalyze… read more here.
Keywords: bovine viperin; production polyclonal; polyclonal viperin; expression ... See more keywords
Viperin impairs the innate immune response through the IRAK1-TRAF6-TAK1 axis to promote Mtb infection
Sign Up to like & getrecommendations! Published in 2022 at "Science Signaling"
DOI: 10.1126/scisignal.abe1621
Abstract: Mycobacterium tuberculosis (Mtb) infection is a long-standing public health threat, and the development of host-directed therapy for eradicating Mtb infection requires better insights into Mtb-host interactions. Viperin [virus-inhibitory protein, endoplasmic reticulum–associated, interferon (IFN) inducible] is… read more here.
Keywords: mtb infection; infection; innate immune; response ... See more keywords
Characterization and Transcript Expression Analyses of Atlantic Cod Viperin
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00311
Abstract: Viperin is a key antiviral effector in immune responses of vertebrates including the Atlantic cod (Gadus morhua). Using cloning, sequencing and gene expression analyses, we characterized the Atlantic cod viperin at the nucleotide and hypothetical… read more here.
Keywords: cod viperin; atlantic cod; viperin; expression ... See more keywords
The Interaction Mechanism Between Herpes Simplex Virus 1 Glycoprotein D and Host Antiviral Protein Viperin
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02810
Abstract: Viperin is an interferon-inducible protein that responsible for a variety of antiviral responses to different viruses. Our previous study has shown that the ribonuclease UL41 of herpes simplex virus 1 (HSV-1) can degrade the mRNA… read more here.
Keywords: protein; hsv; interaction; viperin ... See more keywords