Risk compensation after HIV-1 vaccination may accelerate viral adaptation and reduce cost-effectiveness: a modeling study
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DOI: 10.1038/s41598-021-85487-w
Abstract: Pathogen populations can evolve in response to selective pressure from vaccine-induced immune responses. For HIV, models predict that viral adaptation, either via strain replacement or selection on de novo mutation, may rapidly reduce the effectiveness… read more here.
Keywords: adaptation; vaccine; risk compensation; viral adaptation ... See more keywords