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Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.06.009
Abstract: Adeno-associated virus (AAV) is an ideal vector for gene transduction into the central nervous system because of its safety and efficiency. While it is currently widely used for clinical trials and is expected to become…
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Keywords:
gerbil hippocampus;
combination viral;
associated virus;
adeno associated ... See more keywords
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Published in 2024 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.4c00085
Abstract: Nonenveloped viruses employ unique entry mechanisms to breach and infect host cells. Understanding these mechanisms is crucial for developing antiviral strategies. Prevailing perspective suggests that nonenveloped viruses release membrane pore-forming peptides to breach host membranes.…
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Keywords:
dependent membrane;
metastable viral;
viral capsids;
cholesterol dependent ... See more keywords
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Published in 2020 at "Polymer Journal"
DOI: 10.1038/s41428-020-0355-4
Abstract: A variety of chemical approaches for the rational design of artificial proteins and peptides have been developed in recent years for the construction of self-assembled nanocapsules. It was previously found that a synthetic 24-mer β-annulus…
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Keywords:
artificial viral;
annulus peptides;
self assembled;
dressing artificial ... See more keywords
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Published in 2025 at "Mathematical Modelling of Natural Phenomena"
DOI: 10.1051/mmnp/2025024
Abstract: Many viral capsids are icosahedral-like polyhedra whose folding involves a RNA-tethered string of identical proteinaceous capsomeres. The initial configuration of such tethered ccapsomeres can be represented as Dürer nets which are planar graphs of cuts of polyhedra. While there are only…
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Keywords:
rer nets;
viral capsids;
self foldability;
rer net ... See more keywords
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Published in 2017 at "Physical Review E"
DOI: 10.1103/physreve.95.062402
Abstract: We present a Landau theory for large-l orientational phase transitions and apply it to the assembly of icosahedral viral capsids. The theory predicts two distinct types of ordering transitions. Transitions dominated by the l=6,10,12, and…
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Keywords:
phase;
transitions assembly;
phase transitions;
orientational phase ... See more keywords