Viral and cellular translation during SARS-CoV-2 infection.
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DOI: 10.1002/2211-5463.13413
Abstract: SARS-CoV-2 is a betacoronavirus that emerged in China in December 2019 and which is the causative agent of the Covid-19 pandemic. This enveloped virus contains a large positive-sense single-stranded RNA genome. In this review, we… read more here.
Keywords: translation; cov infection; sars cov; translation sars ... See more keywords
KAP1/TRIM28: Transcriptional Activator and/or Repressor of Viral and Cellular Programs?
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DOI: 10.3389/fcimb.2022.834636
Abstract: Several transcriptional and epigenetic regulators have been functionally linked to the control of viral and cellular gene expression programs. One such regulator is Krüppel-associated box (KRAB)-associated protein 1 (KAP1: also named TRIM28 or TIF1β), which… read more here.
Keywords: kap1 trim28; activator repressor; viral cellular;
Global Transcriptome Analyses of Cellular and Viral mRNAs during HAdV-C5 Infection Highlight New Aspects of Viral mRNA Biogenesis and Cytoplasmic Viral mRNA Accumulations
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DOI: 10.3390/v14112428
Abstract: It is well established that human adenoviruses such as species C, types 2 and 5 (HAdV-C2 and HAdV-C5), induce a nearly complete shutoff of host-cell protein synthesis in the infected cell, simultaneously directing very efficient… read more here.
Keywords: mrna; infection; viral mrna; mrna biogenesis ... See more keywords