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Published in 2017 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.1952
Abstract: Viral binding and entry into host cells for various viruses have been studied extensively, yielding a detailed understanding of the overall viral entry process. As cell entry is an essential and requisite process by which…
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Keywords:
screening viral;
surface plasmon;
entry;
plasmon resonance ... See more keywords
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Published in 2017 at "Virologica Sinica"
DOI: 10.1007/s12250-016-3903-5
Abstract: In this study, we characterized a QD-labeled nonenveloped aquareovirus. Our results showed that QDGCRVs maintained their native particle properties and showed excellent infectivity in host cells. To the best of our knowledge, this is the…
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Keywords:
characterization viral;
infection;
infection quantum;
entry infection ... See more keywords
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Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.03.007
Abstract: Abstract Many natural lectins have been reported to have antiviral activity. As some of these have been put forward as potential development candidates for preventing or treating viral infections, we have set out in this…
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Keywords:
reported antiviral;
inhibitors viral;
antiviral lectins;
selective inhibitors ... See more keywords
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Published in 2022 at "Cell Metabolism"
DOI: 10.1016/j.cmet.2022.01.008
Abstract: Coronavirus disease 2019 (COVID-19) represents a systemic disease that may cause severe metabolic complications in multiple tissues including liver, kidney, and cardiovascular system. However, the underlying mechanisms and optimal treatment remain elusive. Our study shows…
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Keywords:
metabolic complications;
covid;
imatinib methazolamide;
viral entry ... See more keywords
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Published in 2021 at "Current Opinion in Pharmacology"
DOI: 10.1016/j.coph.2021.04.006
Abstract: Since the discovery of SARS-CoV-2 in late 2019, intense research efforts on an unprecedented scale have focused on the study of viral entry mechanisms and adaptive immunity. While the identification of ACE2 and other co-receptors…
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Keywords:
research;
organotypic human;
drug;
human vivo ... See more keywords
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Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00155
Abstract: HIV/AIDS continues to pose an enormous burden on global health. Current HIV therapeutics include inhibitors that target the enzymes HIV protease, reverse transcriptase, and integrase, along with viral entry inhibitors that block the initial steps…
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Keywords:
hiv coreceptor;
hiv;
coreceptor;
peptides inhibit ... See more keywords
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Published in 2022 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.1c00658
Abstract: The entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into host cells requires binding of the viral spike glycoprotein to the angiotensin-converting enzyme 2 (ACE2) receptor, which triggers subsequent conformational changes to facilitate viral…
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Keywords:
cov spike;
block sars;
entry;
tricyclic ring ... See more keywords
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Published in 2020 at "Cell Proliferation"
DOI: 10.1111/cpr.12953
Abstract: Using strategy of drug repurposing, antiviral agents against influenza A virus (IAV) and newly emerging SARS‐coronavirus 2 (SARS‐CoV‐2, also as 2019‐nCoV) could be quickly screened out.
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Keywords:
entry influenza;
effect viral;
direct inhibitory;
inhibitory effect ... See more keywords
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Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.04055-22
Abstract: The seasonality of viral diseases in ectotherms is a prevailing phenomenon in the aquatic environment, which causes huge economic losses every year worldwide and hinders sustainable development of the aquaculture industry. Nevertheless, our understanding of…
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Keywords:
temperature dependent;
gcrv;
entry;
viral diseases ... See more keywords
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Published in 2022 at "Respiration"
DOI: 10.1159/000521317
Abstract: Background The novel beta-coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), enters the human body via mucosal surfaces of the upper and/or lower respiratory tract. Viral entry into epithelial cells is mediated via angiotensin-converting enzyme…
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Keywords:
epithelial cells;
viral entry;
sars cov;
cov receptor ... See more keywords
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Published in 2019 at "F1000Research"
DOI: 10.12688/f1000research.19694.1
Abstract: The process of entry into a host cell is a key step in the life cycle of most viruses. In recent years, there has been a significant increase in our understanding of the routes and…
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Keywords:
entry strategy;
targeting viral;
entry;
broad spectrum ... See more keywords