Domperidone inhibits dengue virus infection by targeting the viral envelope protein and nonstructural protein 1
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-87146-w
Abstract: Dengue is a mosquito-borne disease caused by dengue virus (DENV) infection, which remains a major public health concern worldwide owing to the lack of specific treatments or antiviral drugs available. This study investigated the potential… read more here.
Keywords: viral envelope; protein; infection; dengue virus ... See more keywords
Viral and cellular determinants of polarized trafficking of viral envelope proteins from insect-specific and insect-vectored viruses in insect midgut and salivary gland cells
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Virology"
DOI: 10.1128/jvi.00540-24
Abstract: ABSTRACT Systemic viral infection of insects typically begins with the primary infection of midgut epithelial cells (enterocytes) and subsequent transit of the progeny virus in an apical-to-basal orientation into the hemocoel. For insect-vectored viruses, an… read more here.
Keywords: vectored viruses; viral envelope; virus; insect vectored ... See more keywords