Cell-Derived Viral Genes Evolve under Stronger Purifying Selection in Rhadinoviruses
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.00359-18
Abstract: Viruses and hosts have been shown to capture genes from one another as part of the evolutionary arms race. Such genes offer a natural experiment on the effects of evolutionary pressure, since the same gene… read more here.
Keywords: derived viral; genes evolve; host; viral genes ... See more keywords
Longitudinal transcriptomic characterization of viral genes in HSV-1 infected tree shrew trigeminal ganglia
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DOI: 10.1186/s12985-020-01344-8
Abstract: Background Following acute infection, Herpes Simplex virus-1 (HSV-1) establishes lifelong latency and recurrent reactivation in the sensory neurons of trigeminal ganglia (TG). Infected tree shrew differs from mouse and show characteristics similar to human infection.… read more here.
Keywords: trigeminal ganglia; tree shrew; infection; infected tree ... See more keywords
CRISPR Interference Efficiently Silences Latent and Lytic Viral Genes in Kaposi’s Sarcoma-Associated Herpesvirus-Infected Cells
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DOI: 10.3390/v13050783
Abstract: Uncovering viral gene functions requires the modulation of gene expression through overexpression or loss-of-function. CRISPR interference (CRISPRi), a modification of the CRISPR-Cas9 gene editing technology, allows specific and efficient transcriptional silencing without genetic ablation. CRISPRi… read more here.
Keywords: crispr interference; kaposi sarcoma; sarcoma associated; lytic viral ... See more keywords