Infection phase‐dependent dynamics of the viral and host N6‐methyladenosine epitranscriptome in the lifecycle of an oncogenic virus in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28324
Abstract: Dynamic alteration of the epitranscriptome exerts regulatory effects on the lifecycle of oncogenic viruses in vitro. However, little is known about these effects in vivo because of the general lack of suitable animal infection models… read more here.
Keywords: vivo; infection; viral host; lifecycle oncogenic ... See more keywords
Similarity in viral and host promoters couples viral reactivation with host cell migration
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15006
Abstract: Viral–host interactomes map the complex architecture of an evolved arms race during host cell invasion. mRNA and protein interactomes reveal elaborate targeting schemes, yet evidence is lacking for genetic coupling that results in the co-regulation… read more here.
Keywords: viral host; reactivation; host cell; migration ... See more keywords
VIDHOP, viral host prediction with Deep Learning
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaa705
Abstract: Abstract Motivation Zoonosis, the natural transmission of infections from animals to humans, is a far-reaching global problem. The recent outbreaks of Zikavirus, Ebolavirus, and Coronavirus are examples of viral zoonosis, which occur more frequently due… read more here.
Keywords: viral host; deep learning; host; host prediction ... See more keywords
LINE-1 repression in Epstein-Barr virus-associated gastric cancer through viral-host genome interaction.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad203
Abstract: Long INterspersed Element 1 (LINE-1 or L1) acts as a major remodeling force in genome regulation and evolution. Accumulating evidence shows that virus infection impacts L1 expression, potentially impacting host antiviral response and diseases. The… read more here.
Keywords: host genome; viral host; genome interaction; gastric cancer ... See more keywords
LGCA-VHPPI: A local-global residue context aware viral-host protein-protein interaction predictor
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0270275
Abstract: Viral-host protein protein interaction (PPI) analysis is essential to decode the molecular mechanism of viral pathogen and host immunity processes which eventually help to control viral diseases and optimize therapeutics. The state-of-the-art viral-host PPI predictor… read more here.
Keywords: interaction; lgca vhppi; host protein; viral host ... See more keywords
Role of Viral and Host microRNAs in Immune Regulation of Epstein-Barr Virus-Associated Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00367
Abstract: Epstein-Barr virus (EBV) is an oncogenic human herpes virus that was discovered in 1964. Viral non-coding RNAs, such as BamHI-A rightward fragment-derived microRNAs (BART miRNAs) or BamHI-H rightward fragment 1-derived miRNAs (BHRF1 miRNA) in EBV-infected… read more here.
Keywords: viral host; epstein barr; barr virus; host ... See more keywords
Hallmarks of Severe COVID-19 Pathogenesis: A Pas de Deux Between Viral and Host Factors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.912336
Abstract: Two years into Coronavirus Disease 2019 (COVID-19) pandemic, a comprehensive characterization of the pathogenesis of severe and critical forms of COVID-19 is still missing. While a deep dysregulation of both the magnitude and functionality of… read more here.
Keywords: severe covid; host factors; viral host; covid ... See more keywords
MP-VHPPI: Meta predictor for viral host protein-protein interaction prediction in multiple hosts and viruses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.1025887
Abstract: Viral-host protein-protein interaction (VHPPI) prediction is essential to decoding molecular mechanisms of viral pathogens and host immunity processes that eventually help to control the propagation of viral diseases and to design optimized therapeutics. Multiple AI-based… read more here.
Keywords: meta predictor; hosts viruses; viral host; host ... See more keywords
Virus-Derived Small Interfering RNAs Affect the Accumulations of Viral and Host Transcripts in Maize
Sign Up to like & getrecommendations! Published in 2018 at "Viruses"
DOI: 10.3390/v10120664
Abstract: RNA silencing is a conserved surveillance mechanism against invading viruses in plants, which involves the production of virus-derived small interfering RNAs (vsiRNAs) that play essential roles in the silencing of viral RNAs and/or specific host… read more here.
Keywords: virus derived; viral host; derived small; host transcripts ... See more keywords
Special Issue “Viral and Host Factors Driving the Emergence and the Evolution of the SARS-CoV-2 and Other Coronaviruses”
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14081705
Abstract: Two and half years ago, humanity was facing the emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causal agent of the COVID-19 pandemics that significantly impact public health, society and the global… read more here.
Keywords: host factors; issue viral; viral host; emergence ... See more keywords
Viral and host factors associated with outcomes of hepatitis C virus infection (Review).
Sign Up to like & getrecommendations! Published in 2017 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.6351
Abstract: Hepatitis C virus (HCV) infection is a major health issue globally. Owing to the progress made in host genetics and HCV molecular virology, emerging data have suggested that the natural course and treatment response in… read more here.
Keywords: viral host; host factors; infection; factors associated ... See more keywords