Local synthesis of immunosuppressive glucocorticoids in the intestinal epithelium regulates anti-viral immune responses.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2018.08.009
Abstract: The nuclear receptor Small Heterodimer Partner (SHP) is a transcriptional target and inhibitor of Liver Receptor Homolog 1 (LRH-1), the transcriptional regulator of intestinal glucocorticoid (GC) synthesis. The role of SHP in the regulation of… read more here.
Keywords: anti viral; synthesis; immune responses; viral immune ... See more keywords
Biotypes of HIV-associated neurocognitive disorders based on viral and immune pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000825
Abstract: Purpose of review HIV-associated neurocognitive disorders (HAND) continues to be prevalent in people living with HIV despite antiretroviral therapy. However, understanding disease mechanisms and identifying therapeutic avenues has been challenging. One of the challenges is… read more here.
Keywords: hiv associated; neurocognitive disorders; based viral; associated neurocognitive ... See more keywords
Development and Evaluation of Enzyme-Linked Viral Immune Capture Assay for Detection of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.898726
Abstract: The pandemic of COVID-19 was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019 and it has prompted unprecedented research activities for vaccines, therapeutics, and diagnostics. The real-time reverse transcriptase-polymerase chain reaction… read more here.
Keywords: linked viral; enzyme linked; viral immune; detection ... See more keywords
Understanding Viral and Immune Interplay During Vertical Transmission of HIV: Implications for Cure
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DOI: 10.3389/fimmu.2021.757400
Abstract: Despite the significant progress that has been made to eliminate vertical HIV infection, more than 150,000 children were infected with HIV in 2019, emphasizing the continued need for sustainable HIV treatment strategies and ideally a… read more here.
Keywords: transmission; hiv; interplay vertical; viral immune ... See more keywords
Extracellular Vesicles as a Means of Viral Immune Evasion, CNS Invasion, and Glia-Induced Neurodegeneration
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.695899
Abstract: Extracellular vesicles (EVs) are small, membrane-bound vesicles released by cells as a means of intercellular communication. EVs transfer proteins, nucleic acids, and other biologically relevant molecules from one cell to another. In the context of… read more here.
Keywords: extracellular vesicles; means viral; viral immune; neurodegeneration ... See more keywords