EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2018.08.005
Abstract: BACKGROUND With the capacity to modulate gene networks in an environmentally-sensitive manner, the role of epigenetic systems in mental disorders has come under intense investigation. Dysregulation of epigenetic effectors, including microRNAs and histone-modifying enzymes, may… read more here.
Keywords: dysregulated schizophrenia; antipsychotic sensitive; mir 132; pfc ... See more keywords
Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches.
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbab141
Abstract: During the course of a viral infection, virus-host protein-protein interactions (PPIs) play a critical role in allowing viruses to replicate and survive within the host. These interspecies molecular interactions can lead to viral-mediated perturbations of… read more here.
Keywords: network based; network; pathogenic mechanisms; mediated pathogenic ... See more keywords
Viral-Mediated mRNA Degradation for Pathogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Biomedicines"
DOI: 10.3390/biomedicines6040111
Abstract: Cellular RNA decay machinery plays a vital role in regulating gene expression by altering the stability of mRNAs in response to external stresses, including viral infection. In the primary infection, viruses often conquer the host… read more here.
Keywords: infection; pathogenesis; viral mediated; mrna degradation ... See more keywords