Articles with "viral membrane" as a keyword



Role of the Ebola membrane in the protection conferred by the three-mAb cocktail MIL77

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-35964-6

Abstract: MIL77, which has a higher manufacturing capacity than ZMapp, comprises MIL77-1, MIL77-2, and MIL77-3. The mechanisms by which these antibodies inhibit glycoprotein are unclear. Infection by viruses with lipid-bilayer envelopes occurs via the fusion of… read more here.

Keywords: ebola membrane; mil77 mil77; mil77; viral membrane ... See more keywords
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Maturation of the matrix and viral membrane of HIV-1

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Published in 2021 at "Science"

DOI: 10.1126/science.abe6821

Abstract: Structural changes in HIV maturation Nascent HIV particles assemble at the plasma membrane of an infected cell and bud into a membrane-enveloped, immature virion. Assembly and budding are driven by a polyprotein called Gag, which… read more here.

Keywords: virion; hiv; viral membrane; maturation ... See more keywords
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Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design

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Published in 2017 at "PLoS Pathogens"

DOI: 10.1371/journal.ppat.1006212

Abstract: Among broadly neutralizing antibodies to HIV, 10E8 exhibits greater neutralizing breadth than most. Consequently, this antibody is the focus of prophylactic/therapeutic development. The 10E8 epitope has been identified as the conserved membrane proximal external region… read more here.

Keywords: antibody; viral membrane; therapeutic design; hiv viral ... See more keywords
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Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer

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Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.2210/pdb6cb7/pdb

Abstract: Cellular membranes are maintained as closed compartments, broken up only transiently during membrane reorganization or lipid transportation. However, open-ended membranes, likely derived from scissions of the endoplasmic reticulum, persist in vaccinia virus-infected cells during the… read more here.

Keywords: membrane assembly; viral membrane; lipid bilayer; structure ... See more keywords

Is Lipid Specificity Key to the Potential Antiviral Activity of Mouthwash Reagent Chlorhexidine against SARS-CoV-2?

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Published in 2022 at "Membranes"

DOI: 10.3390/membranes12060616

Abstract: Chlorhexidine (CHX), a popular antibacterial drug, is widely used for oral health. Emerging pieces of evidence suggest that commercially available chlorhexidine mouthwash formulations are effective in suppressing the spread of SARS-CoV-2, possibly through destabilization of… read more here.

Keywords: chx; chlorhexidine; viral membrane; membrane ... See more keywords