Evidence for Viral mRNA Export from Ebola Virus Inclusion Bodies by the Nuclear RNA Export Factor NXF1
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00900-22
Abstract: Filoviruses such as the Ebola virus (EBOV) cause severe hemorrhagic fevers with high case fatality rates and limited treatment options. The identification of virus-host cell interactions shared among several viruses would represent promising targets for… read more here.
Keywords: viral mrna; ebola virus; inclusion bodies; export ... See more keywords
The Paradoxes of Viral mRNA Translation during Mammalian Orthoreovirus Infection
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13020275
Abstract: De novo viral protein synthesis following entry into host cells is essential for viral replication. As a consequence, viruses have evolved mechanisms to engage the host translational machinery while at the same time avoiding or… read more here.
Keywords: infection; paradoxes viral; viral mrna; mrna translation ... See more keywords
RNA-Binding Proteins as Regulators of Internal Initiation of Viral mRNA Translation
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14020188
Abstract: Viruses are obligate intracellular parasites that depend on the host’s protein synthesis machinery for translating their mRNAs. The viral mRNA (vRNA) competes with the host mRNA to recruit the translational machinery, including ribosomes, tRNAs, and… read more here.
Keywords: rna binding; viral mrna; binding proteins; translation initiation ... See more keywords
Global Transcriptome Analyses of Cellular and Viral mRNAs during HAdV-C5 Infection Highlight New Aspects of Viral mRNA Biogenesis and Cytoplasmic Viral mRNA Accumulations
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14112428
Abstract: It is well established that human adenoviruses such as species C, types 2 and 5 (HAdV-C2 and HAdV-C5), induce a nearly complete shutoff of host-cell protein synthesis in the infected cell, simultaneously directing very efficient… read more here.
Keywords: mrna; infection; viral mrna; mrna biogenesis ... See more keywords