Self-assembled Viral Nanoparticles as Targeted Anticancer Vehicles
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-020-0383-0
Abstract: Viral nanoparticles (VNPs) comprise a variety of mammalian viruses, plant viruses, and bacteriophages, that have been adopted as building blocks and supra-molecular templates in nanotechnology. VNPs demonstrate the dynamic, monodisperse, polyvalent, and symmetrical architectures which… read more here.
Keywords: nanoparticles targeted; assembled viral; self assembled; viral nanoparticles ... See more keywords
Plant viral nanoparticles-based HER2 vaccine: Immune response influenced by differential transport, localization and cellular interactions of particulate carriers.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2016.12.030
Abstract: Cancer vaccines are designed to elicit an endogenous adaptive immune response that can successfully recognize and eliminate residual or recurring tumors. Such approaches can potentially overcome shortcomings of passive immunotherapies by generating long-lived therapeutic effects… read more here.
Keywords: plant viral; transport; viral nanoparticles; immune response ... See more keywords
Non-viral nanoparticles for CRISPR-based genome editing: is it just a simple adaption of what have been developed for nucleic acid delivery?
Sign Up to like & getrecommendations! Published in 2019 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.9b00783
Abstract: Genome-editing technologies hold tremendous potential for treating genetic diseases. However, the efficient and safe delivery of genome-editing elements to the location of interest, and the achievement of specific targeted gene correction without off-target side effect… read more here.
Keywords: genome editing; non viral; crispr based; delivery ... See more keywords