Impact of ADAR-induced editing of minor viral RNA populations on replication and transmission of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2112663119
Abstract: Significance Viral RNA may be edited by enzymes of the ADAR family that deaminate adenosine residues with ensuing A→G mutations. We found multiple A→G mutations in minor viral populations of the SARS-CoV-2 genome. A→G mutations… read more here.
Keywords: viral populations; adar; viral rna; minor viral ... See more keywords
KMCP: accurate metagenomic profiling of both prokaryotic and viral populations by pseudo-mapping
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac845
Abstract: Motivation The growing number of microbial reference genomes enables the improvement of metagenomic profiling accuracy but also imposes greater requirements on the indexing efficiency, database size, and runtime of taxonomic profilers. Additionally, most profilers focus… read more here.
Keywords: metagenomic profiling; kmcp; viral populations; profiling ... See more keywords
Uncultivated Viral Populations Dominate Estuarine Viromes on the Spatiotemporal Scale
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DOI: 10.1128/msystems.01020-20
Abstract: This is the first systematic study about spatial and temporal variation of virioplankton communities in estuaries by using deep metagenomics sequencing. It is among the highest-quality viromic data sets to date, showing remarkably consistent sequencing… read more here.
Keywords: viral populations; quality; chesapeake bay; uncultivated viral ... See more keywords
Genetic Diversity of Viral Populations Associated with Ananas Germplasm and Improvement of Virus Diagnostic Protocols
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11121470
Abstract: Pineapple (Ananas comosus L. [Merr.]) accessions from the U.S. Tropical Plant Genetic Resources and Disease Research (TPGRDR) in Hilo, Hawaii were subjected to RNA-sequencing to study the occurrence of viral populations associated with this vegetatively… read more here.
Keywords: viral populations; genetic diversity; populations associated; diversity ... See more keywords