Chemical shift assignment of the viral protein genome-linked (VPg) from potato virus Y
Sign Up to like & getrecommendations! Published in 2019 at "Biomolecular NMR Assignments"
DOI: 10.1007/s12104-018-9842-3
Abstract: The dysregulation of translation contributes to many pathogenic conditions in humans. Discovering new translational mechanisms is important to understanding the diversity of this process and its potential mechanisms. Such mechanisms can be initially observed in… read more here.
Keywords: protein; genome linked; linked vpg; vpg potato ... See more keywords
Viperin protein inhibits the replication of caprine parainfluenza virus 3 (CPIV 3) by interaction with viral N protein.
Sign Up to like & getrecommendations! Published in 2020 at "Antiviral research"
DOI: 10.1016/j.antiviral.2020.104903
Abstract: Caprine parainfluenza virus type3 (CPIV3) is a newly identified member of Paramyxoviridae family. CPIV3 is highly prevalence in China and showed pathogenecity to goats; in addition, CPIV3 infection causes severe clinical disease under stress and/or… read more here.
Keywords: protein; cpiv3; viperin; viral protein ... See more keywords
Conditional potency is a hallmark of viral protein-derived toxic peptides.
Sign Up to like & getrecommendations! Published in 2017 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2017.01.005
Abstract: Viral infections are major ongoing challenges to mankind. The theory of cytokine storm cannot fully account for the virulence of some highly infectious viruses with high mortality rates. Although numerous viruses are capable of lysing… read more here.
Keywords: protein derived; derived toxic; viral protein; conditional potency ... See more keywords
MORC3 Is a Target of the Influenza A Viral Protein NS1.
Sign Up to like & getrecommendations! Published in 2019 at "Structure"
DOI: 10.1016/j.str.2019.03.015
Abstract: Microrchidia 3 (MORC3), a human ATPase linked to several autoimmune disorders, has been characterized both as a negative and positive regulator of influenza A virus. Here, we report that the CW domain of MORC3 (MORC3-CW)… read more here.
Keywords: protein; morc3 target; target influenza; protein ns1 ... See more keywords
HSV-2 glycoprotein J promotes viral protein expression and virus spread.
Sign Up to like & getrecommendations! Published in 2018 at "Virology"
DOI: 10.1016/j.virol.2018.09.004
Abstract: HSV-2 spread is predominantly dependent on cell-to-cell contact. However, the underlying mechanisms remain to be determined. Here we demonstrate that HSV-2 gJ, which was previously assigned no specific function, promotes HSV-2 cell-to-cell spread and syncytia… read more here.
Keywords: protein expression; hsv; expression; viral protein ... See more keywords
Discovery of Potent and Broad-Spectrum Pyrazolopyridine-Containing Antivirals against Enteroviruses D68, A71, and Coxsackievirus B3 by Targeting the Viral 2C Protein.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00758
Abstract: The enterovirus genus of the picornavirus family contains many important human pathogens. EV-D68 primarily infects children, and the disease manifestations range from respiratory illnesses to neurological complications such as acute flaccid myelitis (AFM). EV-A71 is… read more here.
Keywords: d68 a71; potent broad; pyrazolopyridine containing; viral protein ... See more keywords
De novo designed EBAI as a potential inhibitor of the viral protein BHRF1. Research in silico
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2053746
Abstract: Abstract Epstein-Barr virus is a DNA-containing virus that, according to current data, is associated with approximately 1% of all cancers in the world. This viral effect on the human body is associated with its pronounced… read more here.
Keywords: protein bhrf1; inhibitor viral; potential inhibitor; inhibitor ... See more keywords
A Quantitative System for Monitoring Blood-Circulating Viral Protein R of Human Immunodeficiency Virus-1 Detected a Possible Link with Pathogenic Indices.
Sign Up to like & getrecommendations! Published in 2019 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2019.0016
Abstract: We developed a detergent-free enzyme-linked immunosorbent assay (ELISA) for HIV-1 viral protein R (Vpr), an accessory protein of human immunodeficiency virus type-1 (HIV), and detected soluble Vpr in ∼22% of HIV patients who were receiving… read more here.
Keywords: viral protein; immunodeficiency virus; hiv; protein human ... See more keywords
Cytomegalovirus and cardiovascular disease: a hypothetical role for viral G protein-coupled receptors in hypertension.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of hypertension"
DOI: 10.1093/ajh/hpad045
Abstract: Cytomegalovirus (CMV) is a member of the β- herpesviruses and is ubiquitous, infecting 50-99% of the human population depending on ethnic and socioeconomic conditions. CMV establishes lifelong, latent infections in their host. Spontaneous reactivation of… read more here.
Keywords: hypertension; cytomegalovirus; coupled receptors; viral protein ... See more keywords
Expression of the Vaccinia Virus Antiapoptotic F1 Protein Is Blocked by Protein Kinase R in the Absence of the Viral E3 Protein
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.01167-18
Abstract: Previous studies have shown that E3-deficient vaccinia virus triggers apoptosis of infected cells. Our study demonstrates that this proapoptotic phenotype stems, at least in part, from the failure of the mutant virus to produce adequate… read more here.
Keywords: viral protein; virus; vaccinia virus; apoptosis ... See more keywords
Phosphorylated viral protein evades plant immunity through interfering the function of RNA-binding protein
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010412
Abstract: Successful pathogen infection in plant depends on a proper interaction between the invading pathogen and its host. Post-translational modification (PTM) plays critical role(s) in plant-pathogen interaction. However, how PTM of viral protein regulates plant immunity… read more here.
Keywords: plant immunity; infection; protein; viral protein ... See more keywords