Punctuated Loci on Chromosome IV Determine Natural Variation in Orsay Virus Susceptibility of Caenorhabditis elegans Strains Bristol N2 and Hawaiian CB4856
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virology"
DOI: 10.1128/jvi.02430-20
Abstract: Genetic variation determines the viral susceptibility of hosts. Yet, pinpointing which genetic variants determine viral susceptibility remains challenging. Here, we have exploited the genetic tractability of the model organism Caenorhabditis elegans to dissect the genetic… read more here.
Keywords: viral susceptibility; susceptibility; orsay virus; variation ... See more keywords
JAK Signaling Is Critically Important in Cytokine-Induced Viral Susceptibility of Keratinocytes
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119243
Abstract: Little is known about whether type 1 (IFNγ), 2 (IL-4/IL-13), or 3 (IL-17A/IL-22) cytokines affect the susceptibility of keratinocytes (KC) to viruses. These immune pathways predominate in various skin diseases: lupus, atopic dermatitis (AD), and… read more here.
Keywords: cytokine; inhibition; susceptibility keratinocytes; viral susceptibility ... See more keywords
The Viral Susceptibility of the Haloferax Species
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DOI: 10.3390/v14061344
Abstract: Viruses can infect members of all three domains of life. However, little is known about viruses infecting archaea and the mechanisms that determine their host interactions are poorly understood. Investigations of molecular mechanisms of viral… read more here.
Keywords: susceptibility haloferax; viral susceptibility; haloferax; haloferax species ... See more keywords
Why do Individuals Differ in Viral Susceptibility? A Story Told by Model Organisms
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DOI: 10.3390/v9100284
Abstract: Viral susceptibility and disease progression is determined by host genetic variation that underlies individual differences. Genetic polymorphisms that affect the phenotype upon infection have been well-studied for only a few viruses, such as HIV-1 and… read more here.
Keywords: differ viral; susceptibility; viral susceptibility; model organisms ... See more keywords