Activation of viral transcription by stepwise largescale folding of an RNA virus genome
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa675
Abstract: Abstract The genomes of RNA viruses contain regulatory elements of varying complexity. Many plus-strand RNA viruses employ largescale intra-genomic RNA-RNA interactions as a means to control viral processes. Here, we describe an elaborate RNA structure… read more here.
Keywords: activation viral; transcription; viral transcription; rna ... See more keywords
The CCCTC-binding factor CTCF represses hepatitis B virus enhancer I and regulates viral transcription
Sign Up to like & getrecommendations! Published in 2020 at "Cellular microbiology"
DOI: 10.1111/cmi.13274
Abstract: Hepatitis B virus (HBV) infection is of global importance with over 2 billion people exposed to the virus during their lifetime and at risk of progressive liver disease, cirrhosis and hepatocellular carcinoma. HBV is a… read more here.
Keywords: ccctc binding; transcription; viral transcription; hepatitis virus ... See more keywords
Human T-Cell Lymphotropic Virus Type 1 Transactivator Tax Exploits the XPB Subunit of TFIIH during Viral Transcription
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Virology"
DOI: 10.1128/jvi.02171-19
Abstract: HTLV-1 is considered the most potent human oncovirus and is also responsible for severe inflammatory disorders. HTLV-1 transcription is undertaken by RNA polymerase II and is controlled by the viral oncoprotein Tax. Tax transactivates the… read more here.
Keywords: xpb; htlv; transcription; promoter ... See more keywords
Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010532
Abstract: Ebola virus (EBOV) VP35 is a polyfunctional protein involved in viral genome packaging, viral polymerase function, and host immune antagonism. The mechanisms regulating VP35’s engagement in different functions are not well-understood. We previously showed that… read more here.
Keywords: ebola virus; viral transcription; ubiquitination; vp35 ... See more keywords