Detection of hepatitis C virus (HCV) RNA in the peripheral blood mononuclear cells of HCV-infected patients following sustained virologic response
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DOI: 10.1007/s10238-022-00791-7
Abstract: It is unclear whether direct-acting antiviral drugs (DAAs) result in the complete eradication of HCV infection or whether some quantities of the virus may persist after achieving a sustained virologic response (SVR). Aim The aim… read more here.
Keywords: hcv rna; virologic response; rna peripheral; hcv ... See more keywords
Incidence and risk factors of hepatocellular carcinoma change over time in patients with hepatitis C virus infection who achieved sustained virologic response
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DOI: 10.1111/hepr.13310
Abstract: In patients with chronic hepatitis C, hepatocellular carcinoma (HCC) occurs at a certain frequency, even if a sustained virologic response (SVR) is achieved by antiviral treatment. Old age, liver fibrosis, and high post‐treatment α‐fetoprotein (AFP)… read more here.
Keywords: hepatocellular carcinoma; virologic response; sustained virologic; risk factors ... See more keywords
aMAP score prediction of hepatocellular carcinoma occurrence and incidence‐free rate after a sustained virologic response in chronic hepatitis C
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology Research"
DOI: 10.1111/hepr.13689
Abstract: Hepatocellular carcinoma (HCC) can still occur in hepatitis C virus (HCV) patients who have achieved a sustained virologic response (SVR), which remains an important clinical issue in the direct‐acting antivirals era. The current study investigated… read more here.
Keywords: hepatocellular carcinoma; hepatitis; sustained virologic; virologic response ... See more keywords
Durability of virologic response, risk of de novo hepatocellular carcinoma, liver function and stiffness 2 years after treatment with ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in the AMBER, real‐world experience study
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DOI: 10.1111/jvh.12945
Abstract: We followed for 2 years patients treated with direct‐acting agents (DAA) to assess long‐term durability of virologic response, improvement of liver function, reduction in liver stiffness (LS) and risk of hepatocellular carcinoma (HCC). The study… read more here.
Keywords: hepatocellular carcinoma; treatment; study; liver ... See more keywords
Positive predictive value of sustained virologic response 4 weeks posttreatment for achieving sustained virologic response 12 weeks posttreatment in patients receiving glecaprevir/pibrentasvir in Phase 2 and 3 clinical trials
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DOI: 10.1111/jvh.13600
Abstract: Sustained virologic response at posttreatment Week 12 (SVR12) is the widely accepted efficacy endpoint for direct‐acting antiviral agents. Those with hepatitis C virus (HCV) are presenting younger with milder liver disease, potentially reducing need for… read more here.
Keywords: response weeks; sustained virologic; virologic response; clinical trials ... See more keywords
Serum sphingolipids predict de novo hepatocellular carcinoma in hepatitis C cirrhotic patients with sustained virologic response
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DOI: 10.1111/liv.14178
Abstract: Curing hepatitis C virus (HCV) infection reduces the risk of hepatocellular carcinoma (HCC) development, yet HCC occurs despite sustained virologic response (SVR) in 2%‐8% of cirrhotic patients. Sphingolipids (SLs) have been identified as new biomarkers… read more here.
Keywords: hepatocellular carcinoma; hepatitis; cirrhotic patients; sustained virologic ... See more keywords
Virologic response with 2 different cidofovir dosing regimens for preemptive treatment of adenovirus DNAemia in pediatric solid organ transplant recipients
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DOI: 10.1111/petr.13231
Abstract: ADV is frequently seen in our pediatric SOT population. It presents in a variety of clinical presentation and can cause severe disease. In this population, there are very few studies to determine the safety of… read more here.
Keywords: response different; dosing regimens; virologic response; cidofovir dosing ... See more keywords
Cryoglobulinemic Vasculitis Associated with Monoclonal Gammopathy of Undetermined Significance Developed after Sustained Virologic Response of Hepatitis C: A Case Report.
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DOI: 10.2169/internalmedicine.9768-22
Abstract: A 72-year-old woman had a history of chronic hepatitis C virus (HCV) infection previously treated with interferon to achieve a sustained virologic response. Thereafter, she developed polyarthritis and purpura of the lower extremities as well… read more here.
Keywords: virologic response; gammopathy undetermined; undetermined significance; monoclonal gammopathy ... See more keywords
Effects of Achieving Sustained Virologic Response after Direct-Acting Antiviral Agents on Long-Term Liver Fibrosis in Diabetics vs. in Non-Diabetic Patients with Chronic Hepatitis C Infection
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DOI: 10.3390/biomedicines10092093
Abstract: Because of the prevalence of HCV worldwide as well as its undiagnosed population due to a lack of screening, HCV can be considered a modern pandemic disease. In 2016, the World Health Organization (WHO) set… read more here.
Keywords: virologic response; infection; hcv; direct acting ... See more keywords
Real-world effectiveness of direct-acting antivirals in people living with human immunodeficiency virus and hepatitis C virus genotype 6 infections
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DOI: 10.3748/wjg.v28.i11.1172
Abstract: BACKGROUND Hepatitis C virus (HCV) genotype 6 (HCV-6) infection is prevalent predominantly in Southeast Asia, and the data on the virologic response of HCV-6 to direct-acting antivirals (DAAs) are sparse in people living with human… read more here.
Keywords: plwh; virologic response; hcv; hepatitis virus ... See more keywords