Impact of low‐level viraemia on virological failure among Asian children with perinatally acquired HIV on first‐line combination antiretroviral treatment: a multicentre, retrospective cohort study
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DOI: 10.1002/jia2.25550
Abstract: The clinical relevance of low‐level viraemia (LLV) and virological outcomes among children living with HIV (CLHIV) remains controversial. This study aimed to determine the impact of LLV on virological failure (VF) among Asian CLHIV on… read more here.
Keywords: first line; virological failure; among asian; failure among ... See more keywords
Prevalence and patterns of HIV drug resistance in patients with suspected virological failure in North-Western Tanzania
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DOI: 10.1093/jac/dkab406
Abstract: Abstract Background More than 15 million people in sub-Saharan Africa receive ART. Treatment failure is common, but the role of HIV drug resistance in treatment failure is largely unknown because drug resistance testing is not… read more here.
Keywords: suspected virological; drug resistance; virological failure; failure ... See more keywords
A Low Level of Darunavir Resistance–Associated Mutation Emergence in Patients With Virological Failure During Long-term Use of Darunavir in People With HIV. The ANRS CO3 Aquitaine Cohort
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DOI: 10.1093/ofid/ofaa567
Abstract: Abstract Background Ritonavir-boosted darunavir (DRV/r) is a protease inhibitor (PI) indicated for the treatment of naïve and pretreated HIV-infected patients since 2007. Our study aims to describe DRV/r-treated patients experiencing virological failure (VF) documented with… read more here.
Keywords: anrs co3; virological failure; drv; cohort ... See more keywords
Gynoid Fat Distribution and Adipocyte Trapping May Explain Virological Failure With Intramuscular Long-Acting Cabotegravir and Rilpivirine
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DOI: 10.1093/ofid/ofad217
Abstract: Abstract Intramuscular long-acting antiretroviral drugs can improve adherence to lifelong antiretroviral treatment. Nevertheless, adipose tissue thickness and distribution play a critical role with injectable drugs. We describe a virological failure with cabotegravir and rilpivirine in… read more here.
Keywords: long acting; cabotegravir rilpivirine; virological failure; gynoid fat ... See more keywords
Retreatment for hepatitis C virus direct‐acting antiviral therapy virological failure in primary and tertiary settings: The REACH‐C cohort
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DOI: 10.1111/jvh.13705
Abstract: Virological failure occurs in a small proportion of people treated for hepatitis C virus (HCV) with direct‐acting antiviral (DAA) therapies. This study assessed retreatment for virological failure in a large real‐world cohort. REACH‐C is an… read more here.
Keywords: retreatment; failure; primary tertiary; hepatitis virus ... See more keywords
Antiretroviral therapy uptake and predictors of virological failure in patients with HIV receiving first-line and second-line regimens in Johannesburg, South Africa: a retrospective cohort data analysis
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DOI: 10.1136/bmjopen-2021-054019
Abstract: Objective This study described the demographics, treatment information and identified characteristics associated with virological failure and being lost to follow-up (LTFU) for patients with HIV on first-line and second-line antiretroviral therapy (ART) regimens in a… read more here.
Keywords: line regimens; virological failure; second line; cohort ... See more keywords
Virological failure among adolescents on ART, Harare City, 2017- a case-control study
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DOI: 10.1186/s12879-018-3372-6
Abstract: BackgroundZimbabwe is on track towards achieving viral suppression among adults (87%). However, adolescents have only achieved 44% by 2016. In Harare city, 57% of adolescents had attained viral suppression after 12 months on ART compared to… read more here.
Keywords: failure; virological failure; case control; harare city ... See more keywords
Magnitude and associated factors of virological failure among children on ART in Bahir Dar Town public health facilities, Northwest Ethiopia: a facility based cross-sectional study
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DOI: 10.1186/s13052-021-01030-7
Abstract: Background Despite the rapid scale-up of antiretroviral therapy, virologic failure has become global public health concern and challenge, especially in developing countries. Viral load monitoring is an important approach to identify treatment failure and develop… read more here.
Keywords: virological failure; study; failure among; public health ... See more keywords
High rate of virological failure and low rate of switching to second-line treatment among adolescents and adults living with HIV on first-line ART in Myanmar, 2005-2015
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DOI: 10.1371/journal.pone.0171780
Abstract: Background The number of people living with HIV on antiretroviral treatment (ART) in Myanmar has been increasing rapidly in recent years. This study aimed to estimate rates of virological failure on first-line ART and switching… read more here.
Keywords: line; first line; virological failure; art ... See more keywords
Virological failure and all-cause mortality in HIV-positive adults with low-level viremia during antiretroviral treatment
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DOI: 10.1371/journal.pone.0180761
Abstract: Objective Although most HIV-infected individuals achieve undetectable viremia during antiretroviral therapy (ART), a subset have low-level viremia (LLV) of varying duration and magnitude. The impact of LLV on treatment outcomes is unclear. We investigated the… read more here.
Keywords: cause mortality; viremia; virological failure; llv 200 ... See more keywords
Incidence, survival time and associated factors of virological failure among adult HIV/AIDS patients on first line antiretroviral therapy in St. Paul’s Hospital Millennium Medical College—A retrospective cohort study
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DOI: 10.1371/journal.pone.0275204
Abstract: Introduction Human Immune deficiency Virus or Acquired Immune deficiency Syndrome (HIV/AIDS) is a pandemic affecting millions around the world. The 2020 the Joint United Nations Programme on HIV/AIDS report stated that the estimated number of… read more here.
Keywords: time; failure; hiv aids; hospital ... See more keywords