Hepatocellular carcinoma after a sustained virological response by direct‐acting antivirals harbors TP53 inactivation
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DOI: 10.1002/cam4.4571
Abstract: The genomic characteristics of hepatocellular carcinoma (HCC) after a sustained virological response (SVR) and its differences according to whether an SVR was achieved by treatment with direct‐acting antivirals (DAA) or interferon (IFN) are still not… read more here.
Keywords: sustained virological; hepatocellular carcinoma; acting antivirals; direct acting ... See more keywords
Sustained virological response after treatment with direct antiviral agents in individuals with HIV and hepatitis C co‐infection
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DOI: 10.1002/jia2.26048
Abstract: Randomized trials and observational studies have consistently reported rates of sustained virological response (SVR), equivalent to hepatitis C virus (HCV) cure, as high as 95% following treatment with direct‐acting antiviral (DAA) treatment in individuals with… read more here.
Keywords: sustained virological; individuals hiv; infection; treatment direct ... See more keywords
Durability of the virological response after lamivudine discontinuation in lamivudine‐resistant patients with a complete virological response after lamivudine and adefovir combination therapy
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DOI: 10.1002/jmv.24616
Abstract: We investigated the durability of virological response after lamivudine (LAM) discontinuation in LAM‐resistant chronic hepatitis B (CHB) patients with complete virological response after LAM‐adefovir (ADV) combination therapy. We enrolled 58 patients switched to ADV monotherapy… read more here.
Keywords: virological response; combination; lamivudine; response lamivudine ... See more keywords
Impact of obesity on antiretroviral pharmacokinetics and immuno-virological response in HIV-infected patients: a case–control study
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DOI: 10.1093/jac/dkw527
Abstract: Background Obesity has high prevalence among HIV-infected patients. Increased adipose tissue mass affects the pharmacokinetics of numerous drugs, but few data are available for antiretroviral drugs. Objectives In this study we aimed to explore the… read more here.
Keywords: virological response; immuno virological; normal weight; infected patients ... See more keywords
Immuno-virological response and associated factors amongst HIV-1 vertically infected adolescents in Yaoundé-Cameroon
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DOI: 10.1371/journal.pone.0187566
Abstract: Introduction Limited studies have reported the outcomes of lifelong antiretroviral therapy (ART) amongst adolescents living with HIV (ALWHIV) in resource-limited settings (RLS), thus classifying this population as underserved. We therefore aimed to ascertain the immunological… read more here.
Keywords: virological response; response; factors amongst; art ... See more keywords
Rapid virological response of telaprevir and boceprevir in a Brazilian cohort of HCV genotype 1 patients: a multicenter longitudinal study
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DOI: 10.2147/tcrm.s124663
Abstract: Background Chronic hepatitis C is a major public health issue, but there is a gap in the literature regarding the effectiveness and safety of direct-acting antiviral agents in the Brazilian population. The main aim of… read more here.
Keywords: virological response; hcv; study; boceprevir ... See more keywords
Ledipasvir/Sofosbuvir is Effective for Relapsed Genotype 1b Hepatitis C Virus Patients after Achieving a Sustained Virological Response at Post-treatment Week 12 with Glecaprevir/Pibrentasvir.
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DOI: 10.2169/internalmedicine.0865-22
Abstract: A patient with genotype 1b chronic hepatitis C virus who had been treated with pegylated interferon and ribavirin (RBV) was treated with glecaprevir/pibrentasvir (GLE/PIB) for 12 weeks. A sustained virological response at post-treatment week 12… read more here.
Keywords: sustained virological; glecaprevir pibrentasvir; hepatitis virus; treatment ... See more keywords
Sustained viral response and relapse after discontinuation of oral antiviral drugs in HBeAg-positive patients with chronic hepatitis B infection
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DOI: 10.3389/fimmu.2022.1082091
Abstract: Objective To investigate the sustained virological response and relapse in chronic hepatitis B (CHB) patients with hepatitis B e antigen (HBeAg) positive after stopping oral antiviral drugs, and to monitor the disease progression and the… read more here.
Keywords: sustained virological; hbeag positive; relapse; treatment ... See more keywords
Interleukin 28B Polymorphism as a Predictor of Sustained Virological Response to Sofosbuvir-Based Therapy for Hepatitis C Virus Patients
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DOI: 10.3390/tropicalmed7090230
Abstract: In various genome-wide correlation studies, interleukin (IL)28B gene polymorphism has been strongly correlated with both the therapeutic and spontaneous mediated clearance of hepatitis C virus (HCV). Therefore, this study aimed to evaluate the genotype and… read more here.
Keywords: sustained virological; group; hepatitis; treatment ... See more keywords
Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals
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DOI: 10.3748/wjg.v24.i11.1269
Abstract: AIM To determine steatosis and fibrosis prevalence in hepatitis C patients after a sustained virological response achieved with direct-acting antivirals. METHODS Transient elastography with controlled attenuation parameter (CAP) was used to assess hepatic steatosis post-sustained… read more here.
Keywords: virological response; fibrosis; post svr; kpa ... See more keywords
Sustained Virological Response by Direct Antiviral Agents in HCV Leads to an Early and Significant Improvement of Liver Fibrosis
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DOI: 10.3851/imp3186
Abstract: Background Direct antiviral agents (DAA) demonstrated high efficacy among HCV-infected patients in registered trials. Nevertheless, the impact of these therapies on liver stiffness measurement (LSM) and liver functionality in ‘real-life’ is not well-known. The aim… read more here.
Keywords: virological response; improvement; direct antiviral; liver ... See more keywords