BIWT: a bioinformatics walkthrough for embedding spatial multiomics in agent-based models for virtual cells
Sign Up to like & getrecommendations! Published in 2025 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaf571
Abstract: Abstract Summary Whereas transcriptomic and spatial profiling offer static snapshots of tissue structure, mechanistic models use biological rules to predict how tissues evolve. We present the BioInformatics WalkThrough (BIWT) software to directly initialize spatial agent-based… read more here.
Keywords: bioinformatics walkthrough; virtual cells; based models; agent based ... See more keywords
Evolution of evolvability and phenotypic plasticity in virtual cells
Sign Up to like & getrecommendations! Published in 2017 at "BMC Evolutionary Biology"
DOI: 10.1186/s12862-017-0918-y
Abstract: BackgroundChanging environmental conditions pose a challenge for the survival of species. To meet this challenge organisms adapt their phenotype by physiological regulation (phenotypic plasticity) or by evolving. Regulatory mechanisms that ensure a constant internal environment… read more here.
Keywords: evolution; virtual cells; evolvability; change ... See more keywords