Quantitative Map of β-Lactone-Induced Virulence Regulation.
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DOI: 10.1021/acs.jproteome.6b00705
Abstract: β-Lactones have recently been introduced as the first selective ClpP inhibitors that attenuate virulence of both sensitive Staphylococcus aureus and multiresistant strains (MRSA). Although previous knockout studies showed that ClpP is essential for S. aureus… read more here.
Keywords: lactone; virulence; toxin; virulence regulation ... See more keywords