Virus‐Based Nanoparticles of Simian Virus 40 in the Field of Nanobiotechnology
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology Journal"
DOI: 10.1002/biot.201700619
Abstract: Biomolecular nanostructures derived from living organisms, such as protein cages, fibers, and layers are drawing increasing interests as natural biomaterials. The virus‐based nanoparticles (VNPs) of simian virus 40 (SV40), with a cage‐like structure assembled from… read more here.
Keywords: based nanoparticles; virus based; field; nanobiotechnology ... See more keywords
Injectable Slow-Release Hydrogel Formulation of a Plant Virus-Based COVID-19 Vaccine Candidate.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00112
Abstract: Cowpea mosaic virus (CPMV) is a potent immunogenic adjuvant and epitope display platform for the development of vaccines against cancers and infectious diseases, including coronavirus disease 2019. However, the proteinaceous CPMV nanoparticles are rapidly degraded… read more here.
Keywords: plant virus; release; virus based; cpmv ... See more keywords
Comparison of Dendritic Cell Activation by Virus-Based Vaccine Delivery Vectors Emphasizes the Transcriptional Downregulation of the Oxidative Phosphorylation Pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Human gene therapy"
DOI: 10.1089/hum.2018.161
Abstract: Antigen delivery platforms based on engineered viruses or virus-like particles are currently developed as vaccines against infectious diseases. As the interaction of vaccines with dendritic cells (DCs) shapes the immunological response, we compared the interaction… read more here.
Keywords: virus based; delivery; phosphorylation pathway; cell ... See more keywords
Production of high‐titer transmission‐defective RNA virus‐based episomal vector using tangential flow filtration
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DOI: 10.1111/1348-0421.12831
Abstract: In recent years, viral vector based in vivo gene delivery strategies have achieved a significant success in the treatment of genetic diseases. RNA virus‐based episomal vector lacking viral glycoprotein gene (ΔG‐REVec) is a nontransmissive gene… read more here.
Keywords: vector; virus based; high titer; gene ... See more keywords
Multiplexed promoter and gene editing in wheat using a virus‐based guide RNA delivery system
Sign Up to like & getrecommendations! Published in 2022 at "Plant Biotechnology Journal"
DOI: 10.1111/pbi.13910
Abstract: The low efficiency of genetic transformation and gene editing across diverse cultivars hinders the broad application of CRISPR technology for crop improvement. The development of virus-based methods of CRISPR-Cas system delivery into the plant cells… read more here.
Keywords: system; gene; gene editing; delivery ... See more keywords
Virus-Based Immuno-Oncology Models
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DOI: 10.3390/biomedicines10061441
Abstract: Immunotherapy has been extensively explored in recent years with encouraging results in selected types of cancer. Such success aroused interest in the expansion of such indications, requiring a deep understanding of the complex role of… read more here.
Keywords: oncology; based immuno; immuno oncology; oncology models ... See more keywords
Systems Biology Approaches for the Improvement of Oncolytic Virus-Based Immunotherapies
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DOI: 10.3390/cancers15041297
Abstract: Simple Summary This review provides a roadmap to develop safe and effective OV-based future therapeutics by using several novel synthetic and system biology strategies. Integration of system and synthetic biology can improve the genetic design… read more here.
Keywords: oncolytic virus; systems biology; tumor; virus based ... See more keywords