Virus-Derived Nanoparticles.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9869-2_9
Abstract: Capsid-based virus particles are widely engineered as viral nanoparticles and virus-like nanoparticles. The highly organized and uniform capsid structures make them ideal candidates for both in vitro and in vivo applications such as therapeutic delivery… read more here.
Keywords: virus derived; nanoparticles virus; derived nanoparticles; biology ... See more keywords
Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals
Sign Up to like & getrecommendations! Published in 2018 at "Immunity"
DOI: 10.1016/j.immuni.2018.10.003
Abstract: (Immunity 46, 992–1004.e1–e5; June 20, 2017) The authors noticed two errors in the original versions of Figure 1F and Figure 5B of this article. In Figure 1F, the panel for the a-tubulin immunoblot was incorrect.… read more here.
Keywords: virus derived; immunity; figure; derived small ... See more keywords
From current knowledge to best practice: A primer on Viral diagnostics using deep sequencing of virus-derived small interfering RNAs (vsiRNAs) in infected plants.
Sign Up to like & getrecommendations! Published in 2019 at "Methods"
DOI: 10.1016/j.ymeth.2019.10.009
Abstract: Plants have evolved many defense strategies for combating viral infections. One major surveillance strategy adopted by them is manipulating viral sequences to generate distinct small RNA products via Dicer-like enzymes (DCL), and thereby restricting virus… read more here.
Keywords: virus derived; using deep; derived small; small interfering ... See more keywords
Virus-Derived Peptides for Hepatic Enzyme Delivery.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.0c01222
Abstract: Recently, a lipopeptide derived from the hepatitis B virus (HBV) large surface protein has been developed as an HBV entry inhibitor. This lipopeptide, called MyrcludexB (MyrB), selectively binds to the sodium taurocholate cotransporting polypeptide (NTCP)… read more here.
Keywords: enzyme delivery; hrp; virus derived; hrp myrb ... See more keywords
Mutations in virus-derived small RNAs
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-66374-2
Abstract: RNA viruses exist as populations of genome variants. Virus-infected plants accumulate 21–24 nucleotide small interfering RNAs (siRNAs) derived from viral RNA (virus-derived siRNAs) through gene silencing. This paper describes the profile of mutations in virus-derived… read more here.
Keywords: virus derived; mutations virus; derived sirnas; rna ... See more keywords
Virus-derived circular RNAs populate hepatitis C virus–infected cells
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2313002121
Abstract: Significance The cytoplasmic hepatitis C viral RNA genome is shown to be processed into hundreds of circular RNAs. Some of these circular RNAs contain the viral internal ribosome entry site and are translated to yield… read more here.
Keywords: hepatitis; virus; virus derived; derived circular ... See more keywords
Gene Editing by Ferrying of CRISPR/Cas Ribonucleoprotein Complexes in Enveloped Virus-Derived Particles
Sign Up to like & getrecommendations! Published in 2024 at "Human Gene Therapy"
DOI: 10.1089/hum.2024.105
Abstract: The invention of next-generation CRISPR/Cas gene editing tools, like base and prime editing, for correction of gene variants causing disease, has created hope for in vivo use in patients leading to wider clinical translation. To… read more here.
Keywords: gene editing; crispr cas; virus derived; gene ... See more keywords
Plant Virus-Derived Vectors: Applications in Agricultural and Medical Biotechnology.
Sign Up to like & getrecommendations! Published in 2020 at "Annual review of virology"
DOI: 10.1146/annurev-virology-010720-054958
Abstract: Major advances in our understanding of plant viral genome expression strategies and the interaction of a virus with its host for replication and movement, induction of disease, and resistance responses have been made through the… read more here.
Keywords: virus derived; virology; plant virus; derived vectors ... See more keywords
Rice stripe virus-derived siRNAs play different regulatory roles in rice and in the insect vector Laodelphax striatellus
Sign Up to like & getrecommendations! Published in 2018 at "BMC Plant Biology"
DOI: 10.1186/s12870-018-1438-7
Abstract: BackgroundMost plant viruses depend on vector insects for transmission. Upon viral infection, virus-derived small interfering RNAs (vsiRNAs) can target both viral and host transcripts. Rice stripe virus (RSV) is a persistent-propagative virus transmitted by the… read more here.
Keywords: virus derived; vector; rice; rice stripe ... See more keywords
Interaction between endogenous microRNAs and virus-derived small RNAs controls viral replication in insect vectors
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010709
Abstract: MicroRNAs (miRNAs) play an important role in resisting virus infection in insects. Viruses are recognized by insect RNA interference systems, which generate virus-derived small RNAs (vsRNAs). To date, it is unclear whether viruses employ vsRNAs… read more here.
Keywords: virus derived; insect vectors; rsv; derived small ... See more keywords
Antitumor applications of polyphenol-conjugated turnip mosaic virus-derived nanoparticles.
Sign Up to like & getrecommendations! Published in 2022 at "Nanomedicine"
DOI: 10.2217/nnm-2022-0067
Abstract: Background: Filamentous plant virus-derived nanoparticles are biodegradable and noninfectious to humans. Their structure is also amenable to chemical modifications. They constitute an appealing material for biomedical applications including imaging and drug delivery. We had previously used… read more here.
Keywords: virus derived; derived nanoparticles; tumv nps; turnip mosaic ... See more keywords