Articles with "virus directed" as a keyword



Virus-directed enzyme prodrug therapy and the assessment of the cytotoxic impact of some benzimidazole derivatives

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Published in 2017 at "Tumor Biology"

DOI: 10.1177/1010428317713675

Abstract: Virus-directed enzyme prodrug therapy is one of the major strategy of increasing cytotoxicity of bioreductive agents. This research intended to examine new selected benzimidazole derivatives as a substrate for nitroreductase, the enzyme involved in nitroreduction… read more here.

Keywords: virus directed; enzyme prodrug; prodrug therapy; directed enzyme ... See more keywords