Adapting virus filtration to enable intensified and continuous monoclonal antibody processing
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Progress"
DOI: 10.1002/btpr.3088
Abstract: Ongoing efforts in the biopharmaceutical industry to enhance productivity and reduce manufacturing costs include development of intensified, linked, and/or continuous processes. One approach to improve productivity and process economics of the polishing step (i.e., anion… read more here.
Keywords: filtration; step; virus filtration; concentration ... See more keywords
Process- and Product-Related Foulants in Virus Filtration
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9040155
Abstract: Regulatory authorities place stringent guidelines on the removal of contaminants during the manufacture of biopharmaceutical products. Monoclonal antibodies, Fc-fusion proteins, and other mammalian cell-derived biotherapeutics are heterogeneous molecules that are validated based on the production… read more here.
Keywords: product related; process product; virus filtration; filtration ... See more keywords