An Integrative Approach to Virus-Host Protein-Protein Interactions.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8618-7_8
Abstract: Since cell regulation and protein expression can be dramatically altered upon infection by viruses, studying the mechanisms by which viruses infect cells and the regulatory networks they disrupt is essential to understanding viral pathogenicity. This… read more here.
Keywords: protein; integrative approach; biology; virus host ... See more keywords
SARS-CoV-2 will continue to circulate in the human population: an opinion from the point of view of the virus-host relationship
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation Research"
DOI: 10.1007/s00011-020-01352-y
Abstract: At the population level, the virus-host relationship is not set up to end with the complete elimination of either or both. Pathogen-resistant individuals will always remain in the host population. In turn, the virus can… read more here.
Keywords: virus host; host relationship; population; host ... See more keywords
Large–scale screening of molecules involved in virus–host interaction by specific compounds in Cherax quadricarinatus hematopoietic tissue cells
Sign Up to like & getrecommendations! Published in 2020 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2020.735435
Abstract: Abstract White spot syndrome virus is one of the major pathogens that seriously threaten crustacean aquaculture. However, knowledge about the molecular mechanism of virus–host interaction remains limited. In the present study, a library containing 303… read more here.
Keywords: large scale; host interaction; scale screening; host ... See more keywords
Exploration of invasive mechanisms via global ncRNA-associated virus-host crosstalk.
Sign Up to like & getrecommendations! Published in 2019 at "Genomics"
DOI: 10.1016/j.ygeno.2019.10.002
Abstract: Viral infection is a complex pathogenesis and the underlying molecular mechanisms remain poorly understood. In this study, an integrated multiple resources analysis was performed and showed that the cellular ncRNAs and proteins targeted by viruses… read more here.
Keywords: ncrna associated; global ncrna; via global; associated virus ... See more keywords
Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17189-2
Abstract: Coronavirus Disease-2019 (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. Various studies exist about the molecular mechanisms of viral infection. However, such information is spread across many publications and it is very time-consuming… read more here.
Keywords: medicine; drug repurposing; drug; virus host ... See more keywords
Interaction dynamics and virus-host range for estuarine actinophages captured by epicPCR.
Sign Up to like & getrecommendations! Published in 2021 at "Nature microbiology"
DOI: 10.1038/s41564-021-00873-4
Abstract: Viruses impact microbial diversity, gene flow and function through virus-host interactions. Although metagenomics surveys are rapidly cataloguing viral diversity, methods are needed to capture specific virus-host interactions in situ. Here, we leveraged metagenomics and repurposed… read more here.
Keywords: virus host; host; interaction dynamics; host interactions ... See more keywords
The peripheral and core regions of virus-host network of COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbab169
Abstract: Abstract Two thousand nineteen novel coronavirus SARS-CoV-2, the pathogen of COVID-19, has caused a catastrophic pandemic, which has a profound and widespread impact on human lives and social economy globally. However, the molecular perturbations induced… read more here.
Keywords: core regions; peripheral core; virus host; sars cov ... See more keywords
Deciphering the virus‐to‐prokaryote ratio (VPR): insights into virus–host relationships in a variety of ecosystems
Sign Up to like & getrecommendations! Published in 2017 at "Biological Reviews"
DOI: 10.1111/brv.12271
Abstract: The discovery of the numerical importance of viruses in a variety of (aquatic) ecosystems has changed our perception of their importance in microbial processes. Bacteria and Archaea undoubtedly represent the most abundant cellular life forms… read more here.
Keywords: variety; vpr; virus prokaryote; virus host ... See more keywords
Insights for clinical diagnostic indicators of virus and host in chronic hepatitis B infection
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13260
Abstract: Covalently closed circular DNA (cccDNA), which is stably present in the nucleus of hepatocytes, is an important indicator for evaluating antiviral efficacy. Since cccDNA quantification requires an invasive procedure, serum biological markers that can effectively… read more here.
Keywords: insights clinical; hepatitis; clinical diagnostic; chronic hepatitis ... See more keywords
Triterpenoids manipulate a broad range of virus-host fusion via wrapping the HR2 domain prevalent in viral envelopes
Sign Up to like & getrecommendations! Published in 2018 at "Science Advances"
DOI: 10.1126/sciadv.aau8408
Abstract: Natural triterpenoids, as virus-host fusion inhibitors, exhibit potential in expanding the current repertoire of antiviral agents. A trimer-of-hairpins motif has been identified in triggering virus-cell fusion within a variety of viral envelopes. Chemically manipulating such… read more here.
Keywords: virus host; host fusion; viral envelopes; fusion ... See more keywords
Quantitative Assessment of Nucleocytoplasmic Large DNA Virus and Host Interactions Predicted by Co-occurrence Analyses
Sign Up to like & getrecommendations! Published in 2021 at "mSphere"
DOI: 10.1128/msphere.01298-20
Abstract: NCLDVs can infect a wide range of eukaryotes, although their life cycle is less dependent on hosts compared to other viruses. However, our understanding of NCLDV-host systems is highly limited because few of these viruses… read more here.
Keywords: host interactions; virus host; prediction; occurrence ... See more keywords