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Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0346-8_23
Abstract: The serum virus neutralization (SVN) assay is a serological test used to detect the presence and magnitude of functional systemic antibodies that prevent infectivity of a virus. The SVN assay is a highly sensitive and…
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Keywords:
virus neutralization;
serum;
neutralizing antibodies;
serum virus ... See more keywords
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1
Published in 2017 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2017.06.001
Abstract: Antibodies specific for Rift Valley fever virus (RVFV) can be detected by diverse methods, including ezyme-linked immunosortbent assay (ELISA) and virus neutralization test (VNT). The VNT is superior in sensitivity and specificity and is therefore…
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Keywords:
valley fever;
rift valley;
neutralization test;
fever virus ... See more keywords
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Published in 2018 at "Influenza and Other Respiratory Viruses"
DOI: 10.1111/irv.12591
Abstract: The immunological response to influenza vaccine and/or natural infection is evaluated by serological techniques, the most common being hemagglutination inhibition (HI), single radial hemolysis (SRH), and virus neutralization assays, which is commonly used in a…
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Keywords:
inhibition single;
virus neutralization;
hemagglutination inhibition;
neutralization ... See more keywords
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Published in 2021 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.00193-21
Abstract: Methods designed to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) humoral response include virus neutralization tests to determine antibody neutralization activity. For ease of use and universal applicability, surrogate virus neutralization tests (sVNTs) based…
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Keywords:
virus neutralization;
neutralization;
antibody;
sars cov ... See more keywords
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Published in 2021 at "mBio"
DOI: 10.1128/mbio.02492-20
Abstract: Vaccines and antibody-based therapeutics like convalescent-phase plasma therapy are premised upon inducing or transferring neutralizing antibodies that inhibit SARS-CoV-2 entry into cells. Virus neutralization assays (VNAs) for measuring neutralizing antibody titers (NATs) are an essential…
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Keywords:
virus neutralization;
neutralization;
virus;
antibody ... See more keywords
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2
Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02314-22
Abstract: While the measurement of neutralizing antibodies is considered a valuable tool in assessing protection against SARS-CoV-2, neutralization tests employ live-virus isolates and cell culture, requiring advanced laboratory biosafety levels. Including a large sample panel (over…
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Keywords:
neutralizing antibodies;
live virus;
neutralization;
virus neutralization ... See more keywords
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3
Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.05233-22
Abstract: The humoral immune response plays an important role in virus neutralization. Against PEDV, both IgG and the mucosal immune component IgA play roles in virus neutralization. ABSTRACT Porcine epidemic diarrhea (PED) is a highly contagious…
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Keywords:
iga;
neutralization;
virus neutralization;
igg iga ... See more keywords
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Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1180044
Abstract: SARS-CoV-2 infects human cells via binding of the viral spike glycoprotein to its main cellular receptor, angiotensin-converting enzyme 2 (ACE2). The spike protein-ACE2 receptor interaction is therefore a major target for the development of therapeutic…
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Keywords:
virus neutralization;
neutralization activity;
sars cov;
ace2 ... See more keywords
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Published in 2023 at "Antibodies"
DOI: 10.3390/antib12020035
Abstract: Background: Since sensitivity and specificity vary widely between tests, SARS-CoV-2 serology results should be interpreted with caution. Methods: The study included serum samples from patients who had recovered from COVID-19 (n = 71), individuals vaccinated…
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Keywords:
serology;
neutralization test;
neutralization;
virus neutralization ... See more keywords
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Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12020393
Abstract: The humoral response to the SARS-CoV-2 S protein determines the development of protective immunity against this infection. The standard neutralizing antibodies detection method is a live virus neutralization test. It can be replaced with an…
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Keywords:
rbd;
test;
virus neutralization;
ace2 ... See more keywords
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Published in 2022 at "Life"
DOI: 10.3390/life12122064
Abstract: The SARS-CoV-2 neutralizing antibodies response is the best indicator of effective protection after infection and/or vaccination, but its evaluation requires tedious cell-based experiments using an infectious virus. We analyzed, in 105 patients with various histories…
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Keywords:
cov neutralizing;
neutralization test;
neutralization;
virus neutralization ... See more keywords