Development of a versatile oncolytic virus platform for local intra-tumoural expression of therapeutic transgenes
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DOI: 10.1371/journal.pone.0177810
Abstract: Oncolytic viruses which infect and kill tumour cells can also be genetically modified to express therapeutic genes that augment their anti-cancer activities. Modifying oncolytic viruses to produce effective cancer therapies is challenging as encoding transgenes… read more here.
Keywords: virus platform; tumour cells; development versatile; platform ... See more keywords