Biochemical Screening of Potent Zika Virus Protease Inhibitors.
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DOI: 10.1002/cmdc.202100695
Abstract: As the Zika virus protease is an essential and well-established target for the development of antiviral agents, we here have biochemically screened for inhibitors using a purified recombinantly expressed form of this enzyme. As a… read more here.
Keywords: virus protease; biochemical screening; zika virus; protease inhibitors ... See more keywords
Individual Expression of Hepatitis A Virus 3C Protease Induces Ferroptosis in Human Cells In Vitro
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DOI: 10.3390/ijms22157906
Abstract: Regulated cell death (RCD) is a fundamental process common to nearly all living beings and essential for the development and tissue homeostasis in animals and humans. A wide range of molecules can induce RCD, including… read more here.
Keywords: cell; induces ferroptosis; ferroptosis; hepatitis virus ... See more keywords