MG-132 reduces virus release in Bovine herpesvirus-1 infection
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DOI: 10.1038/s41598-017-13717-1
Abstract: Bovine herpesvirus 1 (BoHV-1) can provoke conjunctivitis, abortions and shipping fever. BoHV-1 infection can also cause immunosuppression and increased susceptibility to secondary bacterial infections, leading to pneumonia and occasionally to death. Herein, we investigated the… read more here.
Keywords: bovine herpesvirus; infection; virus release;
Antiviral Ranpirnase TMR-001 Inhibits Rabies Virus Release and Cell-to-Cell Infection In Vitro
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DOI: 10.3390/v12020177
Abstract: Currently, no rabies virus-specific antiviral drugs are available. Ranpirnase has strong antitumor and antiviral properties associated with its ribonuclease activity. TMR-001, a proprietary bulk drug substance solution of ranpirnase, was evaluated against rabies virus in… read more here.
Keywords: tmr 001; rabies virus; ranpirnase; virus release ... See more keywords
The C-Terminal Domain of RNase H and the C-Terminus Amino Acid Residue Regulate Virus Release and Autoprocessing of a Defective HIV-1 Possessing M50I and V151I Changes in Integrase
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DOI: 10.3390/v14122687
Abstract: Previously, we reported that an HIV-1 variant containing Met-to-Ile change at codon 50 and Val-to-Ile mutation at codon 151 of integrase (IN), HIV(IN:M50I/V151I), was an impaired virus. Despite the mutations being in IN, the virus… read more here.
Keywords: hiv; release; amino acid; virus release ... See more keywords